AZ9567, CAS [[3056570-19-2]]

Produktübersicht

• Artikelname: AZ9567, CAS [[3056570-19-2]]
• Artikelnummer: MCE-HY-162353
• Hersteller Artikelnummer: HY-162353
• Alternativnummer: MCE-HY-162353-10MG,MCE-HY-162353-5MG,MCE-HY-162353-10MMX1ML,MCE-HY-162353-100MG,MCE-HY-162353-50MG,MCE-HY-162353-1MG,MCE-HY-162353-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AZ9567 is an orally active MAT2a inhibitor with a pIC50 of 9.1. AZ9567 binds to MAT2a allosterically, reduces the synthesis of SAM, decreases SDMA levels, and exerts antiproliferative effects on MTAP-knockout cells. AZ9567 depletes SAM, causes methionine accumulation in plasma and tissues, triggers adaptive disorders in one-carbon metabolism, transsulfuration metabolism and lipid metabolism, and induces oxidative stress, hepatic steatosis and lipid homeostasis imbalance. AZ9567 can be used in studies related to MTAP-deficient/deleted cancers[1][2][3].

Produkteigenschaften

• Molekulargewicht: 447.44
• Reinheit: 99.21
• CAS Nummer: [3056570-19-2]
• Formel: C24H19F2N5O2
• Target-Kategorie: Methionine Adenosyltransferase (MAT)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1