PAD4-IN-4 (compound 28) is a potent PAD4 inhibitor (IC50=0.790.09 µM). PAD4-IN-4 improves the tumor immune microenvironment by reshaping neutrophil phenotype, upregulating the proportions of dendritic cells and M1 macrophages, and reducing the amount of myeloid-derived suppressor cells. PAD4-IN-4 can be used for Triple-negative breast cancer research[1].
Molekulargewicht:
567.08
Formel:
C32H31ClN6O2
Target-Kategorie:
Protein Arginine Deiminase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
