PAD4-IN-4 (compound 28) is a potent PAD4 inhibitor (IC50=0.790.09 µM). PAD4-IN-4 improves the tumor immune microenvironment by reshaping neutrophil phenotype, upregulating the proportions of dendritic cells and M1 macrophages, and reducing the amount of myeloid-derived suppressor cells. PAD4-IN-4 can be used for Triple-negative breast cancer research[1].
Molecular Weight:
567.08
Formula:
C32H31ClN6O2
Target:
Protein Arginine Deiminase
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
