AP-4-139B, CAS [[2716909-84-9]]

Produktübersicht

• Artikelname: AP-4-139B, CAS [[2716909-84-9]]
• Artikelnummer: MCE-HY-162567
• Hersteller Artikelnummer: HY-162567
• Alternativnummer: MCE-HY-162567-10MG,MCE-HY-162567-50MG,MCE-HY-162567-25MG,MCE-HY-162567-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AP-4-139B is a blood-brain barrier-permeable HSP70 inhibitor with a IC50 of 180 nM against hHSP70. AP-4-139B binds directly to HSP70 and inhibits its ATPase activity. AP-4-139B promotes Autophagy by increasing the phosphorylation of Beclin-1. AP-4-139B exerts antitumor effects in preclinical models of colorectal cancer and pancreatic ductal adenocarcinoma[1][2].

Produkteigenschaften

• Molekulargewicht: 626.59
• Reinheit: 98.87
• CAS Nummer: [2716909-84-9]
• Formel: C34H33BrN3PS
• Target-Kategorie: Autophagy,Beclin1,HSP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound