MC-ND-18, CAS [[3081572-53-1]]

Produktübersicht

• Artikelname: MC-ND-18, CAS [[3081572-53-1]]
• Artikelnummer: MCE-HY-162588
• Hersteller Artikelnummer: HY-162588
• Alternativnummer: MCE-HY-162588-25MG,MCE-HY-162588-100MG,MCE-HY-162588-50MG,MCE-HY-162588-5MG,MCE-HY-162588-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MC-ND-18 is an ATTEC degrader that degrades NLRP3 via the Autophagy pathway, with a DC50 of 125.5 nM in THP-1 cells. MC-ND-18 exhibits anti-inflammatory activity in a DSS-induced mouse model of colitis. MC-ND-18 can be used for research on inflammatory bowel disease. MC-ND-18 consists of an NLRP3 inhibitor (HY-156121), a linker (HY-W018745), and an LC3 ligand[1].

Produkteigenschaften

• Molekulargewicht: 1051.58
• CAS Nummer: [3081572-53-1]
• Formel: C42H42Br2IN3O9S
• Target-Kategorie: ATTECs,Autophagy,NOD-like Receptor (NLR)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound