MC-ND-18, CAS [[3081572-53-1]]

Product Overview

• Article Name: MC-ND-18, CAS [[3081572-53-1]]
• Biozol Catalog Number: MCE-HY-162588
• Supplier Catalog Number: HY-162588
• Alternative Catalog Number: MCE-HY-162588-25MG,MCE-HY-162588-100MG,MCE-HY-162588-50MG,MCE-HY-162588-5MG,MCE-HY-162588-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MC-ND-18 is an ATTEC degrader that degrades NLRP3 via the Autophagy pathway, with a DC50 of 125.5 nM in THP-1 cells. MC-ND-18 exhibits anti-inflammatory activity in a DSS-induced mouse model of colitis. MC-ND-18 can be used for research on inflammatory bowel disease. MC-ND-18 consists of an NLRP3 inhibitor (HY-156121), a linker (HY-W018745), and an LC3 ligand[1].

Product Properties

• Molecular Weight: 1051.58
• CAS Number: [3081572-53-1]
• Formula: C42H42Br2IN3O9S
• Target: ATTECs,Autophagy,NOD-like Receptor (NLR)

Application Notes

• Application Notes: MCE Product type: Reference compound