Lw13 is a Hsp90-targeting PROTAC and achieves maximum degradation at a concentration of 0.05 µM in Siha cells. Lw13 induces cell apoptosis and exhibits potent anti-tumor activity both in vitro and in vivo(Sturcture Note:(Blue: Cereblon ligand (HY-A0003), Black: linker,Pink: Hsp90 inhibitor SNX-5422 (HY-10213))[1].
Molekulargewicht:
904.97
Formel:
C46H55F3N8O8
Target-Kategorie:
Apoptosis,HSP,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
