CDK8-IN-15, CAS [[2988020-03-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: CDK8-IN-15, CAS [[2988020-03-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-162600
• Hersteller Artikelnummer: HY-162600
• Alternativnummer: MCE-HY-162600-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

CDK8-IN-15 (Compound 46) is a potent CDK8 inhibitors with an IC50 value of 57 nM. It can enhance the thermal stability of CDK8 along with inhibition against NF-kappaB and have favourable selectivity across the CDK family and tyrosine kinase. Additionally, it also demostrates a positive effect in vitro psoriasis model induced by TNF-alpha and alleviats the inflammatory response enhancing the expression of Foxp3 and IL-10, which is promising for research of psoriasis diseases[1].

Produkteigenschaften

• Molekulargewicht: 352.39
• CAS Nummer: [2988020-03-5]
• Formel: C19H20N4O3
• Target-Kategorie: CDK

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound