CDK8-IN-15, CAS [[2988020-03-5]] Preis auf Anfrage

Product Overview

• Article Name: CDK8-IN-15, CAS [[2988020-03-5]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-162600
• Supplier Catalog Number: HY-162600
• Alternative Catalog Number: MCE-HY-162600-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

CDK8-IN-15 (Compound 46) is a potent CDK8 inhibitors with an IC50 value of 57 nM. It can enhance the thermal stability of CDK8 along with inhibition against NF-kappaB and have favourable selectivity across the CDK family and tyrosine kinase. Additionally, it also demostrates a positive effect in vitro psoriasis model induced by TNF-alpha and alleviats the inflammatory response enhancing the expression of Foxp3 and IL-10, which is promising for research of psoriasis diseases[1].

Product Properties

• Molecular Weight: 352.39
• CAS Number: [2988020-03-5]
• Formula: C19H20N4O3
• Target: CDK

Application Notes

• Application Notes: MCE Product type: Reference compound