AZ3137, CAS [[2960179-55-7]]

Produktübersicht

• Artikelname: AZ3137, CAS [[2960179-55-7]]
• Artikelnummer: MCE-HY-162702
• Hersteller Artikelnummer: HY-162702
• Alternativnummer: MCE-HY-162702-25MG,MCE-HY-162702-10MG,MCE-HY-162702-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AZ'3137 is an orally active PROTAC-type androgen receptor (AR) degrader with a DC50 value of 22 nM. AZ'3137 can degrade L702H mutant AR (DC50 of 92 nM). AZ3137 can inhibit cell proliferation of LNCaP, with a GI50 value of 74 nM. AZ3137 can inhibit AR signaling and tumor growth in prostate cancer mice (Pink: AR Ligand (HY-172954), Blue: CRBN ligand (HY-172955), Black: linker (HY-W262798), E3 Ligand+Linker: HY-172956)[1].

Produkteigenschaften

• Molekulargewicht: 801.87
• Reinheit: 99.90
• CAS Nummer: [2960179-55-7]
• Formel: C43H47F4N7O4
• Target-Kategorie: Androgen Receptor,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound