BSJ-5-63 is a potent CDK12, CDK7, CDK9 PROTAC degrader. BSJ-5-63 BSJ-5-63 decreases the protein expression of CDK12, CDK7, CDK9, RNAPII, Cyclin K. BSJ-5-63 decreases the mRNA expression of BRCA1, BRCA2. BSJ-5-63 shows anticancer activity and has the potential for the research of prostate cancer (Pink: ligand for target protein (HY-150948), black: linker (HY-W140827), Blue: E3 ligase ligand (HY-112078))[1].
Molekulargewicht:
1020.78
Reinheit:
99.97
CAS Nummer:
[2519823-37-9]
Formel:
C52H74ClN9O6S2
Target-Kategorie:
CDK,PROTACs
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten