p53-MDM2-IN-6, CAS [[1054506-59-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-162927
Hersteller Artikelnummer:
HY-162927
Alternativnummer:
MCE-HY-162927-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
p53-MDM2-IN-6 (Compound 10a), a LSM-83177 hydrazone analog, is a potent p53-MDM2 inhibitor with an IC50 value of 11.08 µg/mL. p53-MDM2-IN-6 arrests the cell cycle in the S phase and induces early and late Apoptosis with antiproliferative activity against HT29 cell lines with an IC50 value of 10.44 µg/mL. p53-MDM2-IN-6 inhibits p53-MDM2 interaction with increment in p-53 level and decrease the expression of GST enzymes. p53-MDM2-IN-6 is promising for research of colorectal cancer[1].
Molekulargewicht:
327.33
CAS Nummer:
[1054506-59-0]
Formel:
C17H17N3O4
Target-Kategorie:
Apoptosis,MDM-2/p53
Anwendungsbeschreibung:
MCE Product type: Reference compound
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