p53-MDM2-IN-6, CAS [[1054506-59-0]] Preis auf Anfrage

Catalog Number: MCE-HY-162927
Article Name: p53-MDM2-IN-6, CAS [[1054506-59-0]] Preis auf Anfrage
Biozol Catalog Number: MCE-HY-162927
Supplier Catalog Number: HY-162927
Alternative Catalog Number: MCE-HY-162927-1UNIT
Manufacturer: MedchemExpress
Category: Biochemikalien
p53-MDM2-IN-6 (Compound 10a), a LSM-83177 hydrazone analog, is a potent p53-MDM2 inhibitor with an IC50 value of 11.08 µg/mL. p53-MDM2-IN-6 arrests the cell cycle in the S phase and induces early and late Apoptosis with antiproliferative activity against HT29 cell lines with an IC50 value of 10.44 µg/mL. p53-MDM2-IN-6 inhibits p53-MDM2 interaction with increment in p-53 level and decrease the expression of GST enzymes. p53-MDM2-IN-6 is promising for research of colorectal cancer[1].
Molecular Weight: 327.33
CAS Number: [1054506-59-0]
Formula: C17H17N3O4
Target: Apoptosis,MDM-2/p53
Application Notes: MCE Product type: Reference compound