pan-KRAS-IN-5, CAS [[3027172-23-9]]

Produktübersicht

• Artikelname: pan-KRAS-IN-5, CAS [[3027172-23-9]]
• Artikelnummer: MCE-HY-163299
• Hersteller Artikelnummer: HY-163299
• Alternativnummer: MCE-HY-163299-50MG,MCE-HY-163299-25MG,MCE-HY-163299-10MG,MCE-HY-163299-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

pan-KRAS-IN-5 is a pan-KRAS translation inhibitor by targeting 5'-UTR RNA G-quadruplexes (rG4s). pan-KRAS-IN-5 strongly binds to and stabilizes KRAS rG4s, inhibits KRAS translation, and blocks the MAPK and PI3K-AKT pathways. pan-KRAS-IN-5 induces cell cycle arrest, prompts apoptosis in KRAS-driven cancer cells. pan-KRAS-IN-5 inhibits tumor growth and KRAS expression in KRAS-mutant xenograft. KRAS-IN-5 can be used for KRAS-driven cancer research[1].

Produkteigenschaften

• Molekulargewicht: 642.55
• Reinheit: 96.70
• CAS Nummer: [3027172-23-9]
• Formel: C31H36FIN4O2
• Target-Kategorie: Akt,Apoptosis,p38 MAPK,PI3K,Ras

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1