pan-KRAS-IN-5, CAS [[3027172-23-9]]

Product Overview

• Article Name: pan-KRAS-IN-5, CAS [[3027172-23-9]]
• Biozol Catalog Number: MCE-HY-163299
• Supplier Catalog Number: HY-163299
• Alternative Catalog Number: MCE-HY-163299-50MG,MCE-HY-163299-25MG,MCE-HY-163299-10MG,MCE-HY-163299-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

pan-KRAS-IN-5 is a pan-KRAS translation inhibitor by targeting 5'-UTR RNA G-quadruplexes (rG4s). pan-KRAS-IN-5 strongly binds to and stabilizes KRAS rG4s, inhibits KRAS translation, and blocks the MAPK and PI3K-AKT pathways. pan-KRAS-IN-5 induces cell cycle arrest, prompts apoptosis in KRAS-driven cancer cells. pan-KRAS-IN-5 inhibits tumor growth and KRAS expression in KRAS-mutant xenograft. KRAS-IN-5 can be used for KRAS-driven cancer research[1].

Product Properties

• Molecular Weight: 642.55
• Purity: 96.70
• CAS Number: [3027172-23-9]
• Formula: C31H36FIN4O2
• Target: Akt,Apoptosis,p38 MAPK,PI3K,Ras

Application Notes

• Application Notes: MCE Product type: Reference compound1