hAChE-IN-8 (Compound S-12) is a orally effective and selective inhibitor of hAChE (IC50=0.486 µM). hAChE-IN-8 also inhibits BACE-1 (IC50=0.542 µM), and does not inhibit Dyrk1A (IC50>10 µM). hAChE-IN-8 can reduce Abeta aggregation, has good blood-brain barrier penetration. hAChE-IN-8 is mainly used in Alzheimers disease research[1].
Molekulargewicht:
442.47
Formel:
C25H22N4O4
Target-Kategorie:
Cholinesterase (ChE),DYRK
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
