PROTAC CDK4/6 degrader 1, CAS [[3025082-14-5]]

Produktübersicht

• Artikelname: PROTAC CDK4/6 degrader 1, CAS [[3025082-14-5]]
• Artikelnummer: MCE-HY-163786
• Hersteller Artikelnummer: HY-163786
• Alternativnummer: MCE-HY-163786-5MG,MCE-HY-163786-1MG,MCE-HY-163786-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC CDK4/6 degrader 1 (Compound 7f) is a dual degrader for CDK4 and CDK6 with DC50 of 10.5 and 2.5 nM. PROTAC CDK4/6 degrader 1 inhibits the proliferation of cell Jurkat (IC50 is 0.18 µM), arrests the cell cycle at G1 phase and induces apoptosis. (Pink: ligand for target protein YY173 (HY-163787), Black: linker (HY-163788), Blue: ligand for E3 ligase (HY-10984))[1]

Produkteigenschaften

• Molekulargewicht: 789.88
• Reinheit: 98.88
• CAS Nummer: [3025082-14-5]
• Formel: C41H47N11O6
• Target-Kategorie: Apoptosis,CDK,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1