LL-K12-18

Artikelnummer: MCE-HY-163944
Artikelname: LL-K12-18
Artikelnummer: MCE-HY-163944
Hersteller Artikelnummer: HY-163944
Alternativnummer: MCE-HY-163944-50MG,MCE-HY-163944-10MG,MCE-HY-163944-5MG,MCE-HY-163944-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
LL-K12-18 is a two-site molecular glue that enhances the protein-protein interaction of the CDK12-DDB1 complex, stabilizing the CDK12-DDB1 complex and promoting the degradation of cyclin K (EC50=0.37 nM). LL-K12-18 exhibits strong gene transcription inhibition and anti-proliferation effects in tumor cells. LL-K12-18 can be used in cancer research[1].
Molekulargewicht: 559.49
Reinheit: 98.42
Formel: C25H32Cl2N10O
Target-Kategorie: CDK,Molecular Glues
Anwendungsbeschreibung: Reference compound