LL-K12-18

Product Overview

• Article Name: LL-K12-18
• Biozol Catalog Number: MCE-HY-163944
• Supplier Catalog Number: HY-163944
• Alternative Catalog Number: MCE-HY-163944-50MG,MCE-HY-163944-10MG,MCE-HY-163944-5MG,MCE-HY-163944-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

LL-K12-18 is a two-site molecular glue that enhances the protein-protein interaction of the CDK12-DDB1 complex, stabilizing the CDK12-DDB1 complex and promoting the degradation of cyclin K (EC50=0.37 nM). LL-K12-18 exhibits strong gene transcription inhibition and anti-proliferation effects in tumor cells. LL-K12-18 can be used in cancer research[1].

Product Properties

• Molecular Weight: 559.49
• Purity: 98.42
• Formula: C25H32Cl2N10O
• Target: CDK,Molecular Glues

Application Notes

• Application Notes: MCE Product type: Reference compound