TNF-alpha-IN-18, CAS [[1272322-42-5]]

Artikelnummer: MCE-HY-164102
Artikelname: TNF-alpha-IN-18, CAS [[1272322-42-5]]
Artikelnummer: MCE-HY-164102
Hersteller Artikelnummer: HY-164102
Alternativnummer: MCE-HY-164102-50MG,MCE-HY-164102-5MG,MCE-HY-164102-100MG,MCE-HY-164102-25MG,MCE-HY-164102-10MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
TNF-alpha-IN-18 (Compound 61) is an inhibitor for TNF-alpha (IC50 of 1.8 µM), that inhibits TNF signaling pathway through block of NF-kB migration from cytoplasm to nucleus. TNF-alpha-IN-18 exhibits slight cytotoxicity to mouse fibroblast LM cell, with a CC50 >50 µM. TNF-alpha-IN-18 ameliorates the TNF- or Lipopolysaccharide (HY-D1056)-induced sepsis in mouse models. TNF-alpha-IN-18 protects mice from rheumatoid arthritis[1].
Molekulargewicht: 336.67
Reinheit: 98.94
CAS Nummer: [1272322-42-5]
Formel: C16H7ClF2O4
Target-Kategorie: NF-kappaB,TNF Receptor
Anwendungsbeschreibung: Reference compound