TNF-alpha-IN-18, CAS [[1272322-42-5]]

Product Overview

• Article Name: TNF-alpha-IN-18, CAS [[1272322-42-5]]
• Biozol Catalog Number: MCE-HY-164102
• Supplier Catalog Number: HY-164102
• Alternative Catalog Number: MCE-HY-164102-50MG,MCE-HY-164102-5MG,MCE-HY-164102-100MG,MCE-HY-164102-25MG,MCE-HY-164102-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

TNF-alpha-IN-18 (Compound 61) is an inhibitor for TNF-alpha (IC50 of 1.8 µM), that inhibits TNF signaling pathway through block of NF-kB migration from cytoplasm to nucleus. TNF-alpha-IN-18 exhibits slight cytotoxicity to mouse fibroblast LM cell, with a CC50 >50 µM. TNF-alpha-IN-18 ameliorates the TNF- or Lipopolysaccharide (HY-D1056)-induced sepsis in mouse models. TNF-alpha-IN-18 protects mice from rheumatoid arthritis[1].

Product Properties

• Molecular Weight: 336.67
• Purity: 98.94
• CAS Number: [1272322-42-5]
• Formula: C16H7ClF2O4
• Target: NF-kappaB,TNF Receptor

Application Notes

• Application Notes: Reference compound