GTCpFE inhibits IKKalpha/beta in the NF-kappaB pathway with anti-inflammatory activities and blocks p65 nuclear entry, which consists of Dimethyl fumarate (DMF) (HY-17363) linked to Aspirin (ASA) (HY-14654). GTCpFE exhibits selective anti-cancer stem-like cell (CSC) activity by reducing mammosphere growth and the CD44+ CD24- immunophenotype. GTCpFE inhibits breast cancer stem cells, an important NFkappaB- and PGE2-dependent phenotype in aggressive cancers[1][2].
Molekulargewicht:
412.39
CAS Nummer:
[1588866-45-8]
Formel:
C22H20O8
Target-Kategorie:
IKK,NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
