HG-6-63-01, CAS [[2177298-99-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: HG-6-63-01, CAS [[2177298-99-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-164482
• Hersteller Artikelnummer: HY-164482
• Alternativnummer: MCE-HY-164482-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HG-6-63-01 is a type II RET tyrosine kinase inhibitor (TKI). HG-6-63-01 also inhibits REarranged during Transfection (RET) kinase and signaling in human thyroid cancer cell lines carrying oncogenic RET alleles. HG-6-63-01 impairs phosphorylation and signalling of RET oncogenic mutants. HG-6-63-01 blunts proliferation of RET/C634R and RET/M918T-transformed fibroblasts and of RET mutant thyroid cancer cells, which is promising for research of cancers harboring oncogenic activation of RET[1][2].

Produkteigenschaften

• Molekulargewicht: 582.06
• CAS Nummer: [2177298-99-4]
• Formel: C31H31ClF3N5O
• Target-Kategorie: RET

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound