HG-6-63-01, CAS [[2177298-99-4]] Preis auf Anfrage

Product Overview

• Article Name: HG-6-63-01, CAS [[2177298-99-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-164482
• Supplier Catalog Number: HY-164482
• Alternative Catalog Number: MCE-HY-164482-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

HG-6-63-01 is a type II RET tyrosine kinase inhibitor (TKI). HG-6-63-01 also inhibits REarranged during Transfection (RET) kinase and signaling in human thyroid cancer cell lines carrying oncogenic RET alleles. HG-6-63-01 impairs phosphorylation and signalling of RET oncogenic mutants. HG-6-63-01 blunts proliferation of RET/C634R and RET/M918T-transformed fibroblasts and of RET mutant thyroid cancer cells, which is promising for research of cancers harboring oncogenic activation of RET[1][2].

Product Properties

• Molecular Weight: 582.06
• CAS Number: [2177298-99-4]
• Formula: C31H31ClF3N5O
• Target: RET

Application Notes

• Application Notes: MCE Product type: Reference compound