BCN-DOTA-GA, CAS [[2416980-98-6]] Preis auf Anfrage

Produktübersicht

• Artikelname: BCN-DOTA-GA, CAS [[2416980-98-6]] Preis auf Anfrage
• Artikelnummer: MCE-HY-164577
• Hersteller Artikelnummer: HY-164577
• Alternativnummer: MCE-HY-164577-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

BCN-DOTA-GA is a cyclooctyne-linked DOTA chelator and prosthetic group. BCN-DOTA-GA forms a stable complex with 89zirconium when radiolabeled via a two-step basic pH adjustment method at 90C. BCN-DOTA-GA conjugates with PAN-tetrazene via click chemistry at 37C to form a radiolabeled antibody conjugate. BCN-DOTA-GA, when conjugated to panitumumab as BCN-Zr-DOTA-GA-PAN, shows stability in whole human serum for up to 7 days at 37C. BCN-DOTA-GA, when conjugated to panitumumab as BCN-Zr-DOTA-GA-PAN, exhibits kinetic inertness against EDTA challenge.BCN-DOTA-GA can be used for the research of her1-expressing colorectal cancers[1].

Produkteigenschaften

• Molekulargewicht: 694.77
• CAS Nummer: [2416980-98-6]
• Formel: C32H50N6O11
• Target-Kategorie: Biochemical Assay Reagents

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: ADC Related