BCN-DOTA-GA, CAS [[2416980-98-6]] Preis auf Anfrage

Product Overview

• Article Name: BCN-DOTA-GA, CAS [[2416980-98-6]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-164577
• Supplier Catalog Number: HY-164577
• Alternative Catalog Number: MCE-HY-164577-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

BCN-DOTA-GA is a cyclooctyne-linked DOTA chelator and prosthetic group. BCN-DOTA-GA forms a stable complex with 89zirconium when radiolabeled via a two-step basic pH adjustment method at 90C. BCN-DOTA-GA conjugates with PAN-tetrazene via click chemistry at 37C to form a radiolabeled antibody conjugate. BCN-DOTA-GA, when conjugated to panitumumab as BCN-Zr-DOTA-GA-PAN, shows stability in whole human serum for up to 7 days at 37C. BCN-DOTA-GA, when conjugated to panitumumab as BCN-Zr-DOTA-GA-PAN, exhibits kinetic inertness against EDTA challenge.BCN-DOTA-GA can be used for the research of her1-expressing colorectal cancers[1].

Product Properties

• Molecular Weight: 694.77
• CAS Number: [2416980-98-6]
• Formula: C32H50N6O11
• Target: Biochemical Assay Reagents

Application Notes

• Application Notes: MCE Product type: ADC Related