DMTr-2-O-C22-rG (ibu)-3-CE-Phosphoramidite is an RNA phosphoramidite monomer for oligonucleotide synthesis. DMTr-2-O-C22-rG (ibu)-3-CE-Phosphoramidite enables site-specific introduction of 2-O-C22 lipophilic modification at guanosine positions to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2-O-C22-rG (ibu)-3-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipid solubility and tissue uptake efficiency of dsRNA. DMTr-2-O-C22-rG (ibu)-3-CE-Phosphoramidite can be used for the construction and mechanism research of nucleic acid silencing molecules[1].
Molekulargewicht:
1164.50
Reinheit:
98
CAS Nummer:
[2923115-75-5]
Formel:
C66H98N7O9P
Target-Kategorie:
DNA/RNA Synthesis,Phosphoramidites
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten