DMTr-2-O-C22-rA-3-CE-Phosphoramidite is an RNA phosphoramidite monomer. DMTr-2-O-C22-rA-3-CE-Phosphoramidite allows site-specific introduction of a 2-O-C22 lipophilic modification at adenosine positions to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2-O-C22-rA-3-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipophilicity and tissue uptake efficiency of dsRNA. DMTr-2-O-C22-rA-3-CE-Phosphoramidite can be used for the construction and mechanism research of nucleic acid silencing molecules[1].
Molekulargewicht:
1182.52
Reinheit:
98
CAS Nummer:
[2923115-67-5]
Formel:
C69H96N7O8P
Target-Kategorie:
DNA/RNA Synthesis,Phosphoramidites
Anwendungsbeschreibung:
MCE Product type: Oligonucleotides
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten