DMTr-2-O-C22-rA-3-CE-Phosphoramidite is an RNA phosphoramidite monomer. DMTr-2-O-C22-rA-3-CE-Phosphoramidite allows site-specific introduction of a 2-O-C22 lipophilic modification at adenosine positions to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2-O-C22-rA-3-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipophilicity and tissue uptake efficiency of dsRNA. DMTr-2-O-C22-rA-3-CE-Phosphoramidite can be used for the construction and mechanism research of nucleic acid silencing molecules[1].
Molecular Weight:
1182.52
Purity:
98
CAS Number:
[2923115-67-5]
Formula:
C69H96N7O8P
Target:
DNA/RNA Synthesis,Phosphoramidites
Application Notes:
MCE Product type: Oligonucleotides
* VAT and and shipping costs not included. Errors and price changes excepted
