SBI-183 is an orally active inhibitor of QSOX1 (Kd: 20 µM). SBI-183 suppresses the proliferative and invasive phenotype of renal cancer cell lines, including triple negative breast cancer cell line, lung adenocarcinoma cell line and pancreatic ductal adenocarcinoma. SBI-183 inhibits tumor growth in two human xenograft mouse models of renal cell carcinoma in vivo [1].
Molekulargewicht:
296.36
Reinheit:
99.8
CAS Nummer:
[625403-59-0]
Formel:
C18H20N2O2
Target-Kategorie:
Transmembrane Glycoprotein
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
