SBI-183 is an orally active inhibitor of QSOX1 (Kd: 20 µM). SBI-183 suppresses the proliferative and invasive phenotype of renal cancer cell lines, including triple negative breast cancer cell line, lung adenocarcinoma cell line and pancreatic ductal adenocarcinoma. SBI-183 inhibits tumor growth in two human xenograft mouse models of renal cell carcinoma in vivo [1].
Molecular Weight:
296.36
Purity:
99.8
CAS Number:
[625403-59-0]
Formula:
C18H20N2O2
Target:
Transmembrane Glycoprotein
Application Notes:
MCE Product type: Reference compound
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