NIR-BG2 is a near-infrared fluorescent probe targeting senescence-associated beta-galactosidase (SA-beta-Gal). NIR-BG2 is activated by SA-beta-Gal and undergoes hydrolysis to release electrophilic quinone methide that covalently binds to surrounding proteins for in situ labeling, with a 16-fold enhancement of fluorescence signal at 709 nm . NIR-BG2 is promising for research of vivo imaging of cellular senescence[1][2].
Molekulargewicht:
730.81
CAS Nummer:
[3036456-18-2]
Formel:
C42H46F2NO8+
Target-Kategorie:
Fluorescent Dye,Glycosidase
Anwendungsbeschreibung:
MCE Product type: Natural Products
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