Crotonyl-CoA (tetralithium), CAS [[116912-55-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: Crotonyl-CoA (tetralithium), CAS [[116912-55-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-166309
• Hersteller Artikelnummer: HY-166309
• Alternativnummer: MCE-HY-166309-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Crotonyl-CoA tetralithium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetralithium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetralithium acts as a substrate for p300s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetralithium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetralithium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetralithium can be used for the research of LPS-induced inflammatory response[1][2].

Produkteigenschaften

• Molekulargewicht: 863.37
• CAS Nummer: [116912-55-1]
• Formel: C25H40Li4N7O17P3S
• Target-Kategorie: Endogenous Metabolite,Histone Acetyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products