Crotonyl-CoA (tetralithium), CAS [[116912-55-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-166309
Supplier Catalog Number:
HY-166309
Alternative Catalog Number:
MCE-HY-166309-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Crotonyl-CoA tetralithium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetralithium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetralithium acts as a substrate for p300s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetralithium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetralithium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetralithium can be used for the research of LPS-induced inflammatory response[1][2].
Molecular Weight:
863.37
CAS Number:
[116912-55-1]
Formula:
C25H40Li4N7O17P3S
Target:
Endogenous Metabolite,Histone Acetyltransferase
Application Notes:
MCE Product type: Natural Products
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