O-Desmethyl carvedilol-d5, CAS [[1794817-24-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: O-Desmethyl carvedilol-d5, CAS [[1794817-24-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-166478S
• Hersteller Artikelnummer: HY-166478S
• Alternativnummer: MCE-HY-166478S-25MG,MCE-HY-166478S-2.5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: Desmethylcarvedilol-d5, BM-14242-d5

Produktbeschreibung

O-Desmethyl carvedilol-d5 (Desmethylcarvedilol-d5) is deuterium labeled O-Desmethylcarvedilol. O-Desmethylcarvedilol (Desmethylcarvedilol) is an active metabolite of the non-selective beta-adrenergic receptor (beta-AR) antagonist Carvedilol (HY-B0006). O-Desmethylcarvedilol inhibits store-overload-induced calcium release in HEK293 cells expressing the ryanodine receptor 2 (RyR2) R4496C (RyR2R4496C) mutation (IC50 = 7.62 µM). O-Desmethylcarvedilol reduces increases in heart rate and prevents decreases in diastolic blood pressure induced by Isoproterenol (HY-B0468) in conscious rabbits (ED50s = 32 and 5 µg/kg, respectively)[1][2].

Produkteigenschaften

• Molekulargewicht: 397.48
• CAS Nummer: [1794817-24-5]
• Formel: C23H19D5N2O4
• Target-Kategorie: Calcium Channel,Isotope-Labeled Compounds

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Isotope-Labeled Compounds