O-Desmethyl carvedilol-d5, CAS [[1794817-24-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-166478S
Supplier Catalog Number:
HY-166478S
Alternative Catalog Number:
MCE-HY-166478S-25MG,MCE-HY-166478S-2.5MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Desmethylcarvedilol-d5, BM-14242-d5
O-Desmethyl carvedilol-d5 (Desmethylcarvedilol-d5) is deuterium labeled O-Desmethylcarvedilol. O-Desmethylcarvedilol (Desmethylcarvedilol) is an active metabolite of the non-selective beta-adrenergic receptor (beta-AR) antagonist Carvedilol (HY-B0006). O-Desmethylcarvedilol inhibits store-overload-induced calcium release in HEK293 cells expressing the ryanodine receptor 2 (RyR2) R4496C (RyR2R4496C) mutation (IC50 = 7.62 µM). O-Desmethylcarvedilol reduces increases in heart rate and prevents decreases in diastolic blood pressure induced by Isoproterenol (HY-B0468) in conscious rabbits (ED50s = 32 and 5 µg/kg, respectively)[1][2].
Molecular Weight:
397.48
CAS Number:
[1794817-24-5]
Formula:
C23H19D5N2O4
Target:
Calcium Channel,Isotope-Labeled Compounds
Application Notes:
MCE Product type: Isotope-Labeled Compounds
* VAT and and shipping costs not included. Errors and price changes excepted
