Rapastinel (acetate), CAS [[491872-39-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: Rapastinel (acetate), CAS [[491872-39-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-16728A
• Hersteller Artikelnummer: HY-16728A
• Alternativnummer: MCE-HY-16728A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: GLYX-13 (acetate)

Produktbeschreibung

Rapastinel acetate (GLYX-13 acetate) is an N-methyl-D-aspartate (NMDA) receptor modulator with long-acting antidepressant activity. Rapastinel acetate exerts its antidepressant effects by enhancing long-term potentiation (LTP) of synaptic transmission. Rapastinel acetate transiently enhances NMDAR-mediated currents in pyramidal neurons in the hippocampus and medial prefrontal cortex by binding to unique sites on the NMDAR complex. Rapastinel acetate significantly enhanced NMDAR-mediated currents at a concentration of 1 µmol/l and significantly reduced the currents at a concentration of 10 µmol/l. The mechanism of action of Rapastinel acetate is related to the reduction of affinity to intracellular calcium inactivation sites, which provides a theoretical basis for enhancing conductance mediated by NMDAR[1].

Produkteigenschaften

• Molekulargewicht: 473.52
• CAS Nummer: [491872-39-0]
• Formel: C20H35N5O8
• Target-Kategorie: iGluR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound