Rapastinel (acetate), CAS [[491872-39-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-16728A
Supplier Catalog Number:
HY-16728A
Alternative Catalog Number:
MCE-HY-16728A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
GLYX-13 (acetate)
Rapastinel acetate (GLYX-13 acetate) is an N-methyl-D-aspartate (NMDA) receptor modulator with long-acting antidepressant activity. Rapastinel acetate exerts its antidepressant effects by enhancing long-term potentiation (LTP) of synaptic transmission. Rapastinel acetate transiently enhances NMDAR-mediated currents in pyramidal neurons in the hippocampus and medial prefrontal cortex by binding to unique sites on the NMDAR complex. Rapastinel acetate significantly enhanced NMDAR-mediated currents at a concentration of 1 µmol/l and significantly reduced the currents at a concentration of 10 µmol/l. The mechanism of action of Rapastinel acetate is related to the reduction of affinity to intracellular calcium inactivation sites, which provides a theoretical basis for enhancing conductance mediated by NMDAR[1].
Molecular Weight:
473.52
CAS Number:
[491872-39-0]
Formula:
C20H35N5O8
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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