Rapastinel (acetate), CAS [[491872-39-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-16728A
Supplier Catalog Number:
HY-16728A
Alternative Catalog Number:
MCE-HY-16728A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
GLYX-13 (acetate)
Rapastinel (GLYX-13) acetate is a potent NMDAR modulator capable of crossing the blood-brain barrier, and it exhibits extremely high affinity for human NMDAR (EC50=0.0017-9.9 nM). Rapastinel acetate enhances ERK signaling and activates the mTOR pathway, thereby upregulating the expression of BDNF and VGF, and inducing significant neuroplastic changes such as enhanced LTP and increased mature dendritic spine density in the hippocampus. Rapastinel acetate moderately elevates the efflux of dopamine, norepinephrine and 5-HT in the prefrontal cortex, and uniquely avoids side effects of traditional antidepressants such as dissociation, addiction or sedation. Rapastinel acetate is applicable to the research of major depressive disorder and hepatocellular carcinoma[1][2][3][4][5].
Molecular Weight:
473.52
CAS Number:
[491872-39-0]
Formula:
C20H35N5O8
Target:
ERK,iGluR,mTOR
Application Notes:
MCE Product type: Reference compound
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