Pexidartinib, CAS [[1029044-16-3]]

Produktübersicht

• Artikelname: Pexidartinib, CAS [[1029044-16-3]]
• Artikelnummer: MCE-HY-16749
• Hersteller Artikelnummer: HY-16749
• Alternativnummer: MCE-HY-16749-5MG,MCE-HY-16749-200MG,MCE-HY-16749-5G,MCE-HY-16749-10MG,MCE-HY-16749-10MMX1ML,MCE-HY-16749-2G,MCE-HY-16749-500MG,MCE-HY-16749-10G,MCE-HY-16749-1G,MCE-HY-16749-100MG,MCE-HY-16749-20G,MCE-HY-16749-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PLX-3397

Produktbeschreibung

Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity. Pexidartinib has limited permeability to the blood-brain barrier, primarily through ABCB1[1][2][3][4][5][6][7].

Produkteigenschaften

• Molekulargewicht: 417.81
• Reinheit: 99.64
• CAS Nummer: [1029044-16-3]
• Formel: C20H15ClF3N5
• Target-Kategorie: Apoptosis,c-Fms,c-Kit

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound