hAChE-IN-9 (compound 7i) is a selective inhibitor of human acetylcholinesterase (hAChE) with IC50 of 0.05 µM and 2.85 µM for AChE and BChE, respectively. hAChE-IN-9 modulates toxic Abeta oligomer forms into non-toxic ones and has antioxidant and neuroprotective effects against Abeta-induced toxicity. hAChE-IN-9 can be used for the study of Alzheimers disease[1].
Molekulargewicht:
470.89
Formel:
C20H15ClN6O4S
Target-Kategorie:
Amyloid-beta,Cholinesterase (ChE)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
