hAChE-IN-9 (compound 7i) is a selective inhibitor of human acetylcholinesterase (hAChE) with IC50 of 0.05 µM and 2.85 µM for AChE and BChE, respectively. hAChE-IN-9 modulates toxic Abeta oligomer forms into non-toxic ones and has antioxidant and neuroprotective effects against Abeta-induced toxicity. hAChE-IN-9 can be used for the study of Alzheimers disease[1].
Molecular Weight:
470.89
Formula:
C20H15ClN6O4S
Target:
Amyloid-beta,Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound
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