PROTAC EZH2 Degrader-3, CAS [[3098718-46-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC EZH2 Degrader-3, CAS [[3098718-46-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-168131
• Hersteller Artikelnummer: HY-168131
• Alternativnummer: MCE-HY-168131-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC EZH2 Degrader-3 (compound ZJ-20) is a EZH2 PROTAC degrader. PROTAC EZH2 Degrader-3 (5 µM, 24 h) not only potently inhibits the expression of EZH2 protein, but also had a strong inhibits effect on the expression levels of other subunits of PRC2 as well as H3k27me3 protein. PROTAC EZH2 Degrader-3 shows anti-proliferative activity and blocks the cell cycle in the G0-G1 phase and induces cell apoptosis((Blue: cereblon ligand Pomalidomide (HY-10984), Black: linker HY-W361751,Pink: EZH2 inhibitor Tazemetostat (HY-13803))[1].

Produkteigenschaften

• Molekulargewicht: 981.19
• CAS Nummer: [3098718-46-5]
• Formel: C56H68N8O8
• Target-Kategorie: Apoptosis,Histone Methyltransferase,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1