PROTAC EZH2 Degrader-3, CAS [[3098718-46-5]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC EZH2 Degrader-3, CAS [[3098718-46-5]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-168131
• Supplier Catalog Number: HY-168131
• Alternative Catalog Number: MCE-HY-168131-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC EZH2 Degrader-3 (compound ZJ-20) is a EZH2 PROTAC degrader. PROTAC EZH2 Degrader-3 (5 µM, 24 h) not only potently inhibits the expression of EZH2 protein, but also had a strong inhibits effect on the expression levels of other subunits of PRC2 as well as H3k27me3 protein. PROTAC EZH2 Degrader-3 shows anti-proliferative activity and blocks the cell cycle in the G0-G1 phase and induces cell apoptosis((Blue: cereblon ligand Pomalidomide (HY-10984), Black: linker HY-W361751,Pink: EZH2 inhibitor Tazemetostat (HY-13803))[1].

Product Properties

• Molecular Weight: 981.19
• CAS Number: [3098718-46-5]
• Formula: C56H68N8O8
• Target: Apoptosis,Histone Methyltransferase,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound