PROTAC KDM3 degrader-1

Produktübersicht

• Artikelname: PROTAC KDM3 degrader-1
• Artikelnummer: MCE-HY-168593
• Hersteller Artikelnummer: HY-168593
• Alternativnummer: MCE-HY-168593-10MMX1ML,MCE-HY-168593-5MG,MCE-HY-168593-10MG,MCE-HY-168593-25MG,MCE-HY-168593-50MG,MCE-HY-168593-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC KDM3 degrader-1 (Compound 4) is a CRBN-recruiting PROTAC designed based on the IOX1 (HY-12304) scaffold. PROTAC KDM3 degrader-1 selectively degrades the KDM3A and KDM3B proteins, thereby inhibiting the Wnt/beta-catenin signaling pathway. PROTAC KDM3 degrader-1 significantly suppresses the self-renewal capacity of colorectal cancer stem cells and inhibits the growth of colorectal cancer tumors. PROTAC KDM3 degrader-1 is suitable for research on colorectal cancer (Target protein ligand (Pink): HY-12304, linker (Black): HY-22335, Conjugate of E3 ligase ligand and linker: HY-112599, E3 ligase (Blue): HY-41547)[1].

Produkteigenschaften

• Molekulargewicht: 663.67
• Reinheit: 99.07
• Formel: C33H37N5O10
• Target-Kategorie: Histone Demethylase,PROTACs,Wnt,beta-catenin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1