PROTAC KDM3 degrader-1

Product Overview

• Article Name: PROTAC KDM3 degrader-1
• Biozol Catalog Number: MCE-HY-168593
• Supplier Catalog Number: HY-168593
• Alternative Catalog Number: MCE-HY-168593-5MG,MCE-HY-168593-10MMX1ML,MCE-HY-168593-10MG,MCE-HY-168593-50MG,MCE-HY-168593-25MG,MCE-HY-168593-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC KDM3 degrader-1 (Compound 4) is a CRBN-recruiting PROTAC designed based on the IOX1 (HY-12304) scaffold. PROTAC KDM3 degrader-1 selectively degrades the KDM3A and KDM3B proteins, thereby inhibiting the Wnt/beta-catenin signaling pathway. PROTAC KDM3 degrader-1 significantly suppresses the self-renewal capacity of colorectal cancer stem cells and inhibits the growth of colorectal cancer tumors. PROTAC KDM3 degrader-1 is suitable for research on colorectal cancer (Target protein ligand (Pink): HY-12304, linker (Black): HY-22335, Conjugate of E3 ligase ligand and linker: HY-112599, E3 ligase (Blue): HY-41547)[1].

Product Properties

• Molecular Weight: 663.67
• Purity: 99.07
• Formula: C33H37N5O10
• Target: Histone Demethylase,PROTACs,Wnt,beta-catenin

Application Notes

• Application Notes: MCE Product type: Reference compound