PROTAC KSP degrader 1, CAS [[3099825-86-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC KSP degrader 1, CAS [[3099825-86-9]] Preis auf Anfrage
• Artikelnummer: MCE-HY-168725
• Hersteller Artikelnummer: HY-168725
• Alternativnummer: MCE-HY-168725-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC KSP degrader 1 (Compound 21) is a PROTAC Degrader for kinesin spindle protein (KSP), that degrades KSP in HCT-116 with DC50 of 114.8 nM. PROTAC KSP degrader 1 inhibits the proliferation of HCT-116 with IC50 of 10 nM, arrests the cell cycle of HCT-116 at G2/M phase, and induces apoptosis in HCT-116. PROTAC KSP degrader 1 exhibits antitumor efficacy in mouse model[1]. (Blue: Ligand for E3 Ligase Cereblon (HY-103596), Blank: Linker (HY-168726), Pink: Target Protein Ligand (HY-168727))

Produkteigenschaften

• Molekulargewicht: 858.01
• CAS Nummer: [3099825-86-9]
• Formel: C48H51N5O8S
• Target-Kategorie: Apoptosis,Kinesin,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1