LDHA-IN-9 (Compound 1g) is an inhibitor for LDH-A with an IC50 of 25 nM. LDHA-IN-9 inhibits the proliferation of DLD-1 cell (GI50 of 27 µM) through apoptosis induction. LDHA-IN-9 exhibits antitumor activity in mouse model without significant toxicity (25 mg/kg)[1].
Molekulargewicht:
384.26
CAS Nummer:
[862719-04-8]
Formel:
C17H22BrNO4
Target-Kategorie:
Apoptosis,Lactate Dehydrogenase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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