LDHA-IN-9 (Compound 1g) is an inhibitor for LDH-A with an IC50 of 25 nM. LDHA-IN-9 inhibits the proliferation of DLD-1 cell (GI50 of 27 µM) through apoptosis induction. LDHA-IN-9 exhibits antitumor activity in mouse model without significant toxicity (25 mg/kg)[1].
Molecular Weight:
384.26
CAS Number:
[862719-04-8]
Formula:
C17H22BrNO4
Target:
Apoptosis,Lactate Dehydrogenase
Application Notes:
MCE Product type: Reference compound
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