NDM-1 inhibitor-8 (Compound 18b) is the covalent inhibitor for new delhi metallo-beta-lactamase-1 (NDM-1) with an IC50 of 7.03 µM. NDM-1 inhibitor-8 inhibits the drug resistant strains, exhibits synergistic antibacterial effect with the use of Meropenem (HY-13678). NDM-1 inhibitor-8 exhibits anti-infectious activity in mouse models[1].
Molekulargewicht:
647.43
Formel:
C28H23Cl2N3O4SSe
Target-Kategorie:
Bacterial,Beta-lactamase
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
