NDM-1 inhibitor-8 (Compound 18b) is the covalent inhibitor for new delhi metallo-beta-lactamase-1 (NDM-1) with an IC50 of 7.03 µM. NDM-1 inhibitor-8 inhibits the drug resistant strains, exhibits synergistic antibacterial effect with the use of Meropenem (HY-13678). NDM-1 inhibitor-8 exhibits anti-infectious activity in mouse models[1].
Molecular Weight:
647.43
Formula:
C28H23Cl2N3O4SSe
Target:
Bacterial,Beta-lactamase
Application Notes:
MCE Product type: Reference compound
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